For more than two decades, Tiffany Reid’s family has been haunted by her disappearance.

The teen vanished May 17, 2004, launching a years-long quest for her loved ones and forever altering the trajectory of older sister Deiandra Reid’s life, pushing her into advocacy to help other families of murdered and missing indigenous women.

Now, the Dateline: Missing in America podcast is taking a new look at Tiffany’s case in the hopes that new evidence could finally help bring their loved one home.